Background: |
This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED). |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SNIP1 |
Immunogen: |
Fusion protein of human SNIP1 |
Full name: |
Smad nuclear interacting protein 1 |
Synonyms: |
PML1; PMRED |
SwissProt: |
Q8TAD8 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human breast cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
46 kDa |
WB Positive control: |
TM4 cell lysate |
WB Recommended dilution: |
1000-5000 |