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021-54845833/15800441009
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Background: |
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
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Applications: |
ELISA, WB |
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Name of antibody: |
USP14 |
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Immunogen: |
Fusion protein of human USP14 |
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Full name: |
ubiquitin specific peptidase 14 |
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Synonyms: |
TGT |
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SwissProt: |
P54578 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
56 kDa |
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WB Positive control: |
A172 and Jurkat cell lysates |
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WB Recommended dilution: |
500-2000 |
