Background: |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. |
Applications: |
ELISA, WB |
Name of antibody: |
GRIK3 |
Immunogen: |
Synthetic peptide of human GRIK3 |
Full name: |
glutamate ionotropic receptor kainate type subunit 3 |
Synonyms: |
EAA5; GLR7; GLUR7; GluK3; GluR7a |
SwissProt: |
Q13003 |
ELISA Recommended dilution: |
5000-10000 |
WB Positive control: |
Human fetal brain tissue and Human cerebrum tissue lysates |
WB Recommended dilution: |
500-2000 |