兔抗GRIK3多克隆抗体

Background:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

Applications:

ELISA, WB

Name of antibody:

GRIK3

Immunogen:

Synthetic peptide of human GRIK3

Full name:

glutamate ionotropic receptor kainate type subunit 3

Synonyms:

EAA5; GLR7; GLUR7; GluK3; GluR7a

SwissProt:

Q13003

ELISA Recommended dilution:

5000-10000

WB Positive control:

Human fetal brain tissue and Human cerebrum tissue lysates

WB Recommended dilution:

500-2000