Background: |
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
GRB7 |
Immunogen: |
Fusion protein of human GRB7 |
Full name: |
growth factor receptor-bound protein 7 |
SwissProt: |
Q14451 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human tonsil and Human brain |
IHC Recommend dilution: |
50-200 |