兔抗PTHLH多克隆抗体

Background:

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.

Applications:

ELISA, IHC

Name of antibody:

PTHLH

Immunogen:

Fusion protein of human PTHLH

Full name:

parathyroid hormone-like hormone

Synonyms：

HHM, PLP, BDE2, PTHR, PTHRP

SwissProt:

P12272

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer and Human thyroid cancer

IHC Recommend dilution:

25-100