兔抗PROC多克隆抗体

Background:

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Applications:

ELISA, WB, IHC

Name of antibody:

PROC

Immunogen:

Synthetic peptide of human PROC

Full name:

protein C, inactivator of coagulation factors Va and VIIIa

Synonyms:

PC; APC; PROC1; THPH3; THPH4

SwissProt:

P04070

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and Human gastric cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

52 kDa

WB Positive control:

SKOV3 cell lysate

WB Recommended dilution:

500-2000