中文名称: 兔抗PRKAR2B(Ab-113) 多克隆抗体
英文名称: Anti-PRKAR2B(Ab-113) rabbit polyclonal antibody
别 名: PRKAR2; RII-BETA
相关类别: 一抗
储 存: 冷冻(-20℃) 避光
抗 原: PRKAR2B(Ab-113)
宿 主: Rabbit
反应种属: Human Mouse Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. |
Applications: |
WB, IHC |
Name of antibody: |
PRKAR2B(Ab-113) |
Immunogen: |
Synthesized non-phosphopeptide derived from human PKA-R2β around the phosphorylation site of serine 113 (R-A-S(p)-V-C). |
Full name: |
protein kinase, cAMP-dependent, regulatory, type II, beta |
Synonyms: |
PRKAR2; RII-BETA |
SwissProt: |
P31323 |
IHC positive control: |
Human colon carcinoma tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
46 kDa |
WB Positive control: |
HepG2 cells and K562 cells lysates |
WB Recommended dilution: |
500-3000 |