兔抗PPY多克隆抗体

Background:

This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Applications:

ELISA, WB

Name of antibody:

PPY

Immunogen:

Synthetic peptide of human PPY

Full name:

pancreatic polypeptide

Synonyms:

PP; PNP

SwissProt:

P01298

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

11 kDa

WB Positive control:

Rat pancreas tissue lysate

WB Recommended dilution:

1000-5000