中文名称: 兔抗PPP1R12A多克隆抗体
英文名称: Anti-PPP1R12A rabbit polyclonal antibody
别 名: MBS; M130; MYPT1
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: PPP1R12A
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. |
Applications: |
ELISA, WB |
Name of antibody: |
PPP1R12A |
Immunogen: |
Fusion protein of human PPP1R12A |
Full name: |
protein phosphatase 1, regulatory subunit 12A |
Synonyms: |
MBS; M130; MYPT1 |
SwissProt: |
O14974 |
ELISA Recommended dilution: |
1000-2000 |
WB Predicted band size: |
115 kDa |
WB Positive control: |
A172 cells |
WB Recommended dilution: |
200-1000 |