Background:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants.
Applications:
ELISA, IHC
Name of antibody:
GPR132
Immunogen:
Synthetic peptide of human GPR132
Full name:
G protein-coupled receptor 132
Synonyms:
G2A
SwissProt:
Q9UNW8
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human cervical cancer and Human colorectal cancer
IHC Recommend dilution:
25-100