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Background: |
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer By similarity. |
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Applications: |
WB |
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Name of antibody: |
GPR68 |
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Immunogen: |
Synthesized peptide derived from internal of human SPR1. |
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Full name: |
G protein-coupled receptor 68 |
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Synonyms： |
OGR1; GPR12A |
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SwissProt: |
Q15743 |
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WB Predicted band size: |
41 kDa |
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WB Positive control: |
Jurkat cells and Hela cells lysates |
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WB Recommended dilution: |
500-3000 |
