兔抗PKMYT1(Phospho-Ser83)多克隆抗体

Background:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Applications:

IHC

Name of antibody:

PKMYT1(Phospho-Ser83)

Immunogen:

Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1.

Full name:

protein kinase, membrane associated tyrosine/threonine 1

Synonyms：

MYT1; PPP1R126

SwissProt:

Q99640

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100