兔抗PFKFB2多克隆抗体

Background:

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

PFKFB2

Immunogen:

Synthetic peptide of human PFKFB2

Full name:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Synonyms：

PFK-2/FBPase-2

SwissProt:

O60825

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

58 kDa

WB Positive control:

NIH/3T3 cells

WB Recommended dilution:

200-1000