Background: |
This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. |
Applications: |
WB, IHC |
Name of antibody: |
GNAL |
Immunogen: |
Synthesized peptide derived from internal of human GNAL. |
Full name: |
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type |
Synonyms: |
DYT25 |
SwissProt: |
P38405 |
IHC positive control: |
Human brain tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
44 kDa |
WB Positive control: |
LOVO cells lysate |
WB Recommended dilution: |
500-3000 |