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Background: |
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. |
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Applications: |
WB |
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Name of antibody: |
GLRB |
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Immunogen: |
Synthesized peptide derived from internal of human GLRB. |
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Full name: |
glycine receptor, beta |
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Synonyms： |
HKPX2 |
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SwissProt: |
P48167 |
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WB Predicted band size: |
56 kDa |
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WB Positive control: |
A549 cells and K562 cells lysates |
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WB Recommended dilution: |
500-3000 |
