中文名称: 兔抗PDZD3多克隆抗体
英文名称: Anti-PDZD3 rabbit polyclonal antibody
别 名: PDZ domain containing 3; IKEPP; PDZK2; NHERF4
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: PDZD3
反应种属: Human
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]). |
Applications: |
ELISA, IHC |
Name of antibody: |
PDZD3 |
Immunogen: |
Fusion protein of human PDZD3 |
Full name: |
PDZ domain containing 3 |
Synonyms: |
IKEPP; PDZK2; NHERF4 |
SwissProt: |
Q86UT5 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human cervical cancer and Human tonsil |
IHC Recommend dilution: |
25-100 |