Background: |
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
FTO |
Immunogen: |
Fusion protein of human FTO |
Full name: |
fat mass and obesity associated |
Synonyms: |
ALKBH9 |
SwissProt: |
Q9C0B1 |
IHC positive control: |
Human gastric cancer and human liver cancer |
IHC Recommend dilution: |
100-300 |
WB Predicted band size: |
58 kDa |
WB Positive control: |
Human fetal brain tissue |
WB Recommended dilution: |
500-2000 |