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中文名称： 兔抗PDHA1多克隆抗体
英文名称： Anti-PDHA1 rabbit polyclonal antibody
别 名： pyruvate dehydrogenase E1 alpha 1 subunit; PDHA; PDHAD; PHE1A; PDHCE1A
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： PDHA1
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PDHA1 |
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Immunogen: |
Fusion protein of human PDHA1 |
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Full name: |
pyruvate dehydrogenase E1 alpha 1 subunit |
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Synonyms: |
PDHA; PDHAD; PHE1A; PDHCE1A |
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SwissProt: |
P08559 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human cervical cancer and Human tonsil |
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IHC Recommend dilution: |
50-300 |
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WB Predicted band size: |
43 kDa |
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WB Positive control: |
Mouse brain tissue, HepG2, Hela, A549 cell, Mouse skeletal muscle tissue, NIH/3T3 cell lysates |
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WB Recommended dilution: |
1000-5000 |
