兔抗PDE6D多克隆抗体

Background:

This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.

Applications:

ELISA, IHC

Name of antibody:

PDE6D

Immunogen:

Fusion protein of human PDE6D

Full name:

phosphodiesterase 6D

Synonyms:

PDED; JBTS22

SwissProt:

O43924

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

50-100