中文名称: 兔抗UMPS多克隆抗体
Background: |
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
UMPS |
Immunogen: |
Fusion protein of human UMPS |
Full name: |
uridine monophosphate synthetase |
Synonyms: |
OPRT |
SwissProt: |
P11172 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human brain |
IHC Recommend dilution: |
30-150 |