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中文名称 : 兔抗PCSK5多克隆抗体
英文名称 : Anti-PCSK5 rabbit polyclonal antibody
别 名 : proprotein convertase subtilisin/kexin type 5; PC5; PC6; PC6A; SPC6
储 存 : 冷冻（-20℃）
抗 原 : PCSK5
宿 主 : Rabbit
反应种属 : Human, Mouse, Rat
相关类别 : 一抗
标 记 物 : Unconjugate
克隆类型 : rabbit polyclonal
技术规格
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Background: |
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PCSK5 |
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Immunogen: |
Fusion protein of human PCSK5 |
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Full name: |
proprotein convertase subtilisin/kexin type 5 |
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Synonyms: |
PC5; PC6; PC6A; SPC6 |
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SwissProt: |
Q92824 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
25-100 |
