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  • 兔抗PCDHA6多克隆抗体

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    • 品牌 : 通蔚生物
    • 目录号 : TW21253
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称 :   兔抗PCDHA6多克隆抗体


英文名称 :   Anti-PCDHA6 rabbit polyclonal antibody


别       名 :   CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6


抗       原 :   PCDHA6


储       存 :   冷冻(-20℃)


宿       主 : 
Rabbit


相关类别 :  一抗


反应种属 :   Human


标  记 物 :   Unconjugate


克隆类型 :  rabbit polyclonal


技术规格

Background:

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Applications:

ELISA, IHC

Name of antibody:

PCDHA6

Immunogen:

Synthetic peptide of human PCDHA6

Full name:

protocadherin alpha 6

Synonyms:

CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6

SwissProt:

Q9UN73

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human tonsil

IHC Recommend dilution:

10-50