中文名称 : 兔抗PCDHA6多克隆抗体
英文名称 : Anti-PCDHA6 rabbit polyclonal antibody
别 名 : CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
抗 原 : PCDHA6
储 存 : 冷冻(-20℃)
宿 主 : Rabbit
相关类别 : 一抗
反应种属 : Human
标 记 物 : Unconjugate
克隆类型 : rabbit polyclonal
技术规格
Background: |
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. |
Applications: |
ELISA, IHC |
Name of antibody: |
PCDHA6 |
Immunogen: |
Synthetic peptide of human PCDHA6 |
Full name: |
protocadherin alpha 6 |
Synonyms: |
CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6 |
SwissProt: |
Q9UN73 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
10-50 |