中文名称: 兔抗PAK1 (Phospho-Thr212)多克隆抗体
英文名称: Anti-PAK1 (Phospho-Thr212) rabbit polyclonal antibody
别 名: PAKalpha
相关类别: 一抗
储 存: 冷冻(-20℃) 避光
宿 主: Rabbit
抗 原: PAK1 (Phospho-Thr212)
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. |
Applications: |
WB, IHC, IF |
Name of antibody: |
PAK1 (Phospho-Thr212) |
Immunogen: |
Synthetic peptide of human PAK1 (Phospho-Thr212) |
Full name: |
p21 protein (Cdc42/Rac)-activated kinase 1 (Phospho-Thr212) |
Synonyms: |
PAKalpha |
SwissProt: |
Q13153 |
IHC positive control: |
Human breast carcinoma |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
68 kDa |
WB Positive control: |
293 cells untreated or treated with forskolin |
WB Recommended dilution: |
500-1000 |
IF Positive control: |
Hela cells |
IF Recommended dilution |
100-200 |