中文名称: 兔抗NTRK1(Phospho-Tyr757) 多克隆抗体
英文名称: Anti-NTRK1(Phospho-Tyr757) rabbit polyclonal antibody
别 名: MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
相关类别: 一抗
储 存: 冷冻(-20℃) 避光
宿 主: Rabbit
抗 原: NTRK1(Phospho-Tyr757)
反应种属: Human Mouse
标 记 物: Unconjugate
克隆类型: Unconjugate
技术规格
Background: |
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
Applications: |
IHC |
Name of antibody: |
NTRK1(Phospho-Tyr757) |
Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 757 (E-V-Y(p)-A-I) derived from Human Trk A. |
Full name: |
neurotrophic tyrosine kinase, receptor, type 1 |
Synonyms: |
MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA |
SwissProt: |
P04629 |
IHC positive control: |
Human brain tissue |
IHC Recommend dilution: |
50-100 |