兔抗NTAN1多克隆抗体

Background:

The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Applications:

ELISA, IHC

Name of antibody:

NTAN1

Immunogen:

Fusion protein of human NTAN1

Full name:

N-terminal asparagine amidase

Synonyms:

PNAA; PNAD

SwissProt:

Q96AB6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human prostate cancer

IHC Recommend dilution:

40-200