兔抗SEPTIN4多克隆抗体

Background:

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. [provided by RefSeq, Nov 2010]

Applications:

ELISA, IHC

Name of antibody:

SEPTIN4

Immunogen:

Synthetic peptide of human SEPTIN4

Full name:

septin 4

Synonyms:

H5; ARTS; MART; SEP4; CE5B3; SEPT4; PNUTL2; hucep-7; BRADEION; C17orf47; hCDCREL-2

SwissProt:

O43236

IHC positive control:

Human lung cancer and Human thyroid cancer

IHC Recommend dilution:

50-200