兔抗NPM1(Phospho-Thr199)多克隆抗体

Background:

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Applications:

WB

Name of antibody:

NPM1(Phospho-Thr199)

Immunogen:

Peptide sequence around phosphorylation site of Threonine 199 (R-D-T(p)-P-A) derived from Human NPM.

Full name:

nucleophosmin (nucleolar phosphoprotein B23, numatrin)

Synonyms：

B23; NPM

SwissProt:

P06748

WB Predicted band size:

33 kDa

WB Positive control:

Mouse heart tissue lysates

WB Recommended dilution:

500-1000