兔抗NKX2-5多克隆抗体

Background:

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

NKX2-5

Immunogen:

Fusion protein of human NKX2-5

Full name:

NK2 homeobox 5

Synonyms:

CSX; CSX1; VSD3; CHNG5; HLHS2; NKX2E; NKX2.5; NKX4-1

SwissProt:

P52952

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human thyroid cancer

IHC Recommend dilution:

25-100