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中文名称：兔抗SAV1多克隆抗体
英文名称： Anti-SAV1 rabbit polyclonal antibody
别 名： salvador family WW domain containing protein 1; SAV; WW45; WWP4
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原：SAV1
反应种属： Human, Mouse, Rat
标记物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
SAV1 |
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Immunogen: |
Fusion protein of human SAV1 |
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Full name: |
salvador family WW domain containing protein 1 |
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Synonyms: |
SAV; WW45; WWP4 |
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SwissProt: |
Q9H4B6 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain and Human gastric cancer |
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IHC Recommend dilution: |
100-300 |
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WB Predicted band size: |
45 kDa |
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WB Positive control: |
HUVEC, PC-3 cell lysates |
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WB Recommended dilution: |
500-2000 |
