兔抗NFKBIE (Phospho-Ser22)多克隆抗体

Background:

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.

Applications:

WB, IHC

Name of antibody:

NFKBIE (Phospho-Ser22)

Immunogen:

Synthetic peptide of human NFKBIE (Phospho-Ser22)

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (Phospho-Ser22)

Synonyms：

IKBE

SwissProt:

O00221

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

40 kDa

WB Positive control:

293 cells untreated or treated with TNF

WB Recommended dilution:

500-1000