兔抗RRM2B多克隆抗体

Background:

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

Applications:

WB

Name of antibody:

RRM2B

Immunogen:

Synthesized peptide derived from Internal of human RRM2B.

Full name:

ribonucleotide reductase M2 B (TP53 inducible)

Synonyms：

P53R2; MTDPS8A; MTDPS8B

SwissProt:

Q7LG56

WB Predicted band size:

41 kDa

WB Positive control:

COLO205 cells lysate

WB Recommended dilution:

500-3000