兔抗UCP1多克隆抗体

Background:

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Applications:

ELISA, IHC

Name of antibody:

UCP1

Immunogen:

Synthetic peptide of humanUCP1

Full name:

uncoupling protein 1 (mitochondrial, proton carrier)

Synonyms：

UCP; SLC25A7

SwissProt:

P25874

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

30-150