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英文名称： Anti-NCR2 rabbit polyclonal antibody
别 名： LY95; CD336; NKP44; NK-p44; dJ149M18.1
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： NCR2
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene. NCR2 has also been designated as CD336 (cluster of differentiation 336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
NCR2 |
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Immunogen: |
Synthetic peptide of human NCR2 |
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Full name: |
natural cytotoxicity triggering receptor 2 |
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Synonyms： |
LY95; CD336; NKP44; NK-p44; dJ149M18.1 |
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SwissProt: |
O95944 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human liver cancer and Human lung cancer |
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IHC Recommend dilution: |
50-200 |
