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中文名称： 兔抗RNF111多克隆抗体
英文名称： Anti-RNF111 rabbit polyclonal antibody
别 名： ring finger protein 111; ARK; hRNF111
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： RNF111
反应种属： Human, Mouse
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
RNF111 |
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Immunogen: |
Fusion protein of human RNF111 |
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Full name: |
ring finger protein 111 |
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Synonyms: |
ARK; hRNF111 |
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SwissProt: |
Q6ZNA4 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human gastric cancer |
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IHC Recommend dilution: |
50-300 |
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WB Predicted band size: |
109 kDa |
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WB Positive control: |
TM4 cell lysate |
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WB Recommended dilution: |
200-1000 |
