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  • 兔抗RNF20多克隆抗体

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    • 品牌 : 通蔚生物
    • 目录号 : TW20474
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称:兔抗RNF20多克隆抗体

英文名称 Anti-RNF20 rabbit polyclonal antibody

别      名: BRE1; BRE1A; hBRE1

相关类别: 一抗

储      存: 冷冻(-20℃)

宿      主: Rabbit

抗      原: RNF20

反应种属: Human, Mouse

标记物: Unconjugate

克隆类型 rabbit polyclonal


技术规格

Background:

The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.

Applications:

ELISA, WB, IHC

Name of antibody:

RNF20

Immunogen:

Fusion protein of human RNF20

Full name:

ring finger protein 20, E3 ubiquitin protein ligase

Synonyms:

BRE1; BRE1A; hBRE1

SwissProt:

Q5VTR2

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and human colon cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

114 kDa

WB Positive control:

Hela, Jurkat, 231, A375, A172 and Lovo cells

WB Recommended dilution:

500-2000