Background: |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. |
Applications: |
ELISA, WB |
Name of antibody: |
FOS |
Immunogen: |
Fusion protein of human FOS |
Full name: |
Fos proto-oncogene, AP-1 transcription factor subunit |
Synonyms: |
p55; AP-1; C-FOS |
SwissProt: |
P01100 |
ELISA Recommended dilution: |
5000-10000 |
WB Predicted band size: |
41 kDa |
WB Positive control: |
Jurkat cell lysate |
WB Recommended dilution: |
200-1000 |