兔抗FNIP2多克隆抗体

Background:

This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin.

Applications:

ELISA, IHC

Name of antibody:

FNIP2

Immunogen:

Synthetic peptide of human FNIP2

Full name:

folliculin interacting protein 2

Synonyms:

FNIPL; MAPO1

SwissProt:

Q9P278

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

25-100