Background: |
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]). |
Applications: |
WB |
Name of antibody: |
FLT3LG |
Immunogen: |
Synthesized peptide derived from internal of human Flt3 ligand. |
Full name: |
fms-related tyrosine kinase 3 ligand |
Synonyms: |
FL; FLT3L |
SwissProt: |
P49771 |
WB Predicted band size: |
26 kDa |
WB Positive control: |
Jurkat cells lysate |
WB Recommended dilution: |
500-3000 |