Background: |
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
FLNC |
Immunogen: |
Synthetic peptide of human FLNC |
Full name: |
filamin C |
Synonyms: |
ABPA; ABPL; FLN2; MFM5; MPD4; RCM5; CMH26; ABP-280; ABP280A |
SwissProt: |
Q14315 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
291 kDa |
WB Positive control: |
LO2, NIH/3T3, A172 cell lysates |
WB Recommended dilution: |
500-2000 |