Background: |
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
FHL2 |
Immunogen: |
Fusion protein of human FHL2 |
Full name: |
four and a half LIM domains 2 |
Synonyms: |
DRAL; AAG11; FHL-2; SLIM3; SLIM-3 |
SwissProt: |
Q14192 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human cervical cancer and human brain |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
32 kDa |
WB Positive control: |
Mouse heart tissue |
WB Recommended dilution: |
1000-5000 |