Background: |
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described. |
Applications: |
ELISA, WB |
Name of antibody: |
FHL1 |
Immunogen: |
Fusion protein of human FHL1 |
Full name: |
four and a half LIM domains 1 |
Synonyms: |
KYOT; SLIM; FHL-1; FHL1A; FHL1B; FLH1A; SLIM1; XMPMA; SLIM-1; SLIMMER |
SwissProt: |
Q13642 |
ELISA Recommended dilution: |
2000-5000 |
WB Predicted band size: |
36 kDa |
WB Positive control: |
MCF-7 and NIH/3T3 cells |
WB Recommended dilution: |
500-2000 |