Background: |
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
FECH |
Immunogen: |
Synthetic peptide of human FECH |
Full name: |
ferrochelatase |
Synonyms: |
EPP; FCE |
SwissProt: |
P22830 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human cervical cancer |
IHC Recommend dilution: |
50-300 |
WB Predicted band size: |
48 kDa |
WB Positive control: |
K562 cell and Human heart tissue lysates |
WB Recommended dilution: |
500-2000 |