Background: |
Fc fragment of IgE, high affinity I, receptor for, alpha polypeptide, also known as high affinity immunoglobulin epsilon receptor subunit alpha, FCER1A and FCE1A, is a single-pass type I membrane protein which contains 2 immunoglobulin-like domains. FCER1A is a subunit of the IgE receptor, which is composed of one glycosylated alpha (FCER1A), one beta (FCER1B), and two gamma (FCER1G) subunits. The high affinity IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. |
Applications: |
WB |
Name of antibody: |
FCER1A |
Immunogen: |
Fusion protein of human FCER1A |
Full name: |
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
Synonyms: |
FCE1A; FcERI |
SwissProt: |
P12319 |
WB Predicted band size: |
30 kDa |
WB Positive control: |
Mouse spleen tissue |
WB Recommended dilution: |
500-2000 |