兔抗FBXO8多克隆抗体

Background:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

Applications:

ELISA, WB

Name of antibody:

FBXO8

Immunogen:

Fusion protein of human FBXO8

Full name:

F-box protein 8

Synonyms:

FBS; DC10; FBX8

SwissProt:

Q9NRD0

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

37 kDa

WB Positive control:

Raji cell lysate

WB Recommended dilution:

500-2000