Background: |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. |
Applications: |
ELISA, IHC |
Name of antibody: |
FASTK |
Immunogen: |
Fusion protein of human FASTK |
Full name: |
fas-activated serine/threonine kinase |
Synonyms: |
FAST |
SwissProt: |
Q14296 |
IHC positive control: |
Human gastric cancer and human brain |
IHC Recommend dilution: |
50-200 |