Background: |
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. |
Applications: |
WB |
Name of antibody: |
FANCD2(Phospho-Ser222) |
Immunogen: |
Peptide sequence around phosphorylation site of serine 222 (G-D-S(p)-Q-H) derived from Human FANCD2. |
Full name: |
Fanconi anemia, complementation group D2 |
Synonyms: |
FA4; FAD; FACD; FAD2; FA-D2; FANCD |
SwissProt: |
Q9BXW9 |
WB Predicted band size: |
166 kDa |
WB Positive control: |
HT29 cells lysates treated with CalyculinA |
WB Recommended dilution: |
500-1000 |