兔抗FAM111B多克隆抗体

Background:

This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.

Applications:

ELISA, IHC

Name of antibody:

FAM111B

Immunogen:

Synthetic peptide of human FAM111B

Full name:

family with sequence similarity 111 member B

Synonyms:

CANP; POIKTMP

SwissProt:

Q6SJ93

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

30-150