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021-54845833/15800441009
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Background: |
FAM13B is a 915 amino acid protein that is encoded by a gene that maps to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FAM13B |
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Immunogen: |
Synthetic peptide of human FAM13B |
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Full name: |
family with sequence similarity 13, member B |
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Synonyms： |
N61; KHCHP; C5orf5; FAM13B1; ARHGAP49 |
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SwissProt: |
Q9NYF5 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and Human gastric cancer |
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IHC Recommend dilution: |
50-200 |
