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021-54845833/15800441009
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Background: |
FAIM2 (Fas apoptotic inhibitory molecule 2), also known as LFG (Protein lifeguard), TMBIM2 (Transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FAIM2 |
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Immunogen: |
Fusion protein of human FAIM2 |
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Full name: |
Fas apoptotic inhibitory molecule 2 |
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Synonyms： |
LFG; LFG2; NGP35; NMP35; TMBIM2 |
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SwissProt: |
Q9BWQ8 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human cervical cancer and human tonsil |
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IHC Recommend dilution: |
50-200 |
