Background: |
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA. |
Applications: |
ELISA, IHC |
Name of antibody: |
FAAP24 |
Immunogen: |
Synthetic peptide of human FAAP24 |
Full name: |
Fanconi anemia core complex associated protein 24 |
Synonyms: |
C19orf40 |
SwissProt: |
Q9BTP7 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer and Human lung cancer |
IHC Recommend dilution: |
30-150 |